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Carnitine - Diet or Supplement? - Your body needs carnitine for energy production, especially in your muscles, but does taking carnitine supplements give you more energy or aid weight loss? Probably not. And you don't really need to worry about getting enough dietary carnitine because it's found in both animal and plant based foods and your body makes carnitine too, so deficiency is rare. Learn more: CarnitineCarnitine - Diet or Supplement? originally appeared on About.com Nutrition on Monday, May 21st, 2012 at 16:16:15.Permali...
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Nutrition Information for Chicken Breasts - Chicken breast meat is low in fat and has lots of protein. It also has zinc, iron and selenium. Chicken (like any type of protein source) is only healthful as the recipe the uses it. Avoid deep-fried chicken or heavy creams or sauces. Opt for low-fat recipes and baked, grilled or roasted chicken instead: Nutrition Facts for Chicken BreastsImage © Adlife MarketingNutrition Information for Chicken Breasts originally appeared on ...
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Nutrition Information for Sweet Potatoes - Did you know that yams and sweet potatoes are a great source of vitamin A and beta carotene? Sweet potatoes are also a good source of fiber. They have a naturally sweet flavor that doesn't need much extra seasoning, although they're often glazed or served in sweet potato pie. Today I wrote an article about sweet potatoes, how to choose them, how to cook them and I included some links to healthy and delicious recipes that feature sweet potatoes: Nutrition Facts for Sweet Potatoes What's your favorite way to serve sweet potatoes? I like mine baked and then served with a little bit of real maple syrup with a few pecans sprinkled on top.Image © Adlife Marketing...
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Foods High in Vitamin C - Your body needs vitamin C for wound healing, strong blood vessels, healthy skin and for your immune system to function. Currently, the Institute of Medicine recommends around 75 to 90 milligrams of vitamin C per day and you get that amount mostly from fruits and vegetables. You'd normally get your vitamin C from a variety of foods, but just to give you an idea of how much vitamin C certain foods contain, I've got some pictures to show you how much you'd need to eat to get a full day's value of vitamin C . More About Fruits, Vegetables and Vitamin C What Is Vitamin C? ...
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Calorie Calculator Helps You Lose Weight - If you want to lose weight you need to consume fewer calories than what you burn every day. If you want to gain weight, you need to take in more calories every day. If you're happy with your current weight, knowing how many calories you need every day will help you maintain your weight. Use my Calorie Calculator to calculate your calorie need. It will help you figure out how many calories you need to lose weight or gain weight safely.Help for Losing Weight Measure Your Body CompositionHow to Lose Weight Weekend Diet Traps ...
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Coffee Makes You Live Longer? - Well, I love coffee, so I wish that were true. Authors of a new study published in The New England Journal of Medicine claim to have found a correlation between drinking coffee (lots of coffee) and living longer. Studies like this are called observational studies - the researchers didn't force anyone to drink lots of coffee, they simply divided people into groups based on the amount of coffee they drank and looked for any correlations. Correlation is the key word here. Studies like this can find associations, but they're usually not strong enough to point to something (in this case, coffee drinking) as a cause of something else. They also have to try to factor out other things like smoking (coffee drinkers tend to smoke more often, so that sort of association has to be weeded out). So can drinking lots of coffee help you live longer? It's pos...
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Nutrition Information for Quinoa - Quinoa (you pronounce it KEEN-WAH) is an ancient grain from South America. Well, actually it's a seed, but it's a member of the grains and cereals food group. It has a delicious nutty flavor and it's usually served the way you'd serve rice or maybe oatmeal. It's also a great source of dietary minerals like iron and magnesium.Not familiar with quinoa? Here's more about it: Nutrition Facts for QuinoaImage © Sabine Scheckel/Getty ImagesNutrition Information for Quinoa originally appeared on ...
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Academy of Nutrition and Dietetics' Position on Quick Fix Diets - Have you heard of the K-E Diet? It's a low-carb diet, but it's extreme. You don't eat anything, you're fed through a tube that goes through your nose down to your stomach. It's a a quick fix diet. Scary, if you ask me. The Acacemy of Nutrition and Dietetics isn't too keen on this diet either. They don't endorse the diet, but certain websites list them as a source of information. The Academy wants to clarify their position: A website containing information on using the K-E Diet for...
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Types of Bottled Water - Every day I see people drinking bottled water. That's a good thing I think. Water is calorie-free and you need to stay hydrated. Did you know there are four types of bottled water, according to the United States Food and Drug Administration? Artesian well water Mineral water Spring water Well water You may be picturing your bottled water's origin as a crystal clear stream flowing from some spring untouched by humans, but a lot of bottled water is just tap water that's been treated by distillation, reverse osmosis, filtration and ozonation. More About Water How Much Water Do You Need Today? ...
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Nutrition Information for Broccoli - Broccoli is one of those vegetables that most people either love or hate. Except for me. I like broccoli and I eat a lot of it, but I can't say I love broccoli. Of course, when I was a kid, I absolutely hated it, so I guess I've made some progress. Broccoli has some interesting compounds that may be good for your health, plus it has lots of good nutrition. Here's the info: Nutrition Facts for Broccoli. ...
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Effect of a LoBAG30 diet on protein metabolism in men with type 2 diabetes - Background: We previously reported that a weight-maintenance diet with a carbohydrate:protein:fat ratio of 30:30:40%, ingested for 5 weeks, improved blood glucose control in subjects with untreated type 2 diabetes. In this study we also determined that insulin and insulin-like growth factor-I (IGF-I) were increased. In this report we provide further information. Specifically, 24-hour total and individual amino acid, glucagon and cortisol data are provided. In addition, we determined whether these multiple effectors resulted in a positive nitrogen balance and an increase in fat-free mass. Insulin and IGF-I should stimulate protein accumulation. An increase in amino acids, particularly branched chain amino acids should facilitate this, whereas glucagon and cortisol could have adverse effects in this regard. Methods: Eight men with untreated type 2 diabetes were studied. A randomized crossover design was used. Data were obtained before and after 5 weeks on a control diet (55% carbohydrate...
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Serum 25-hydroxyvitamin D3 and body composition in an elderly cohort from Germany: a cross-sectional study - Background: Emerging evidence indicates that there is an association between vitamin D and obesity. The aim of this study was to investigate whether the level of serum 25-hydroxyvitamin D3 [25(OH)D3] in the elderly is influenced by parameters of anthropometry and body composition independent of potential confounding lifestyle factors and the level of serum intact parathyroid hormone (iPTH). Methods: Cross-sectional data of 131 independently living participants (90 women, 41 men; aged 66-96 years) of the longitudinal study on nutrition and health status in senior citizens of Giessen, Germany were analysed. Concentrations of 25(OH)D3 and iPTH were ascertained by an electrochemiluminescence immunoassay. Body composition was measured by a bioelectrical impedance analysis. We performed univariate and multiple regression analyses to examine the influence of body composition on 25(OH)D3 with adjustments for age, iPTH and lifestyle factors. Results: In univariate regression analyses, 25(OH)D3 ...
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Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse. - Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse.Authors: Silvia Fernandez-Roig1, Shao-Chiang Lai2, Michelle M Murphy1, Joan Fernandez-Ballart1, Edward V Quadros2*.Institutional addresses:1Area of Preventive Medicine and Public Health, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili (URV), IISPV, Reus, Spain and CIBER Fisiopatologia de la Obesidad y Nutricion (CB06/03) Instituto Carlos III.2Departments of Medicine and Cell Biology, SUNY Downstate Medical Center, Brooklyn,New York, USA.Email address for all authors:silvia.fernandez@urv.cat ;shao-chiang.lai@downstate.edumichelle.murphy@urv.cat;joan.fernandez-ballart@urv.cat ;edward.quadros@downstate.edu.*Corresponding author:Prof. Edward V Quadros,Department of Medicine,SUNY Downstate Medical Center,Brooklyn, New York, USA.Abstract Background: DNA methylation is an epigenetic phenomenon that can modulate gene function by up or downregulation of gene expression. Vitam...
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Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism - Provision of dietary amino acids increases skeletal muscle protein synthesis (MPS), an effectthat is enhanced by prior resistance exercise. As a fundamentally necessary process in theenhancement of muscle mass, strategies to enhance rates of MPS would be beneficial in thedevelopment of interventions aimed at increasing skeletal muscle mass particularly whencombined with chronic resistance exercise. The purpose of this review article is to provide anupdate on current findings regarding the nutritional regulation of MPS and highlight nutritionbased strategies that may serve to maximize skeletal muscle protein anabolism withresistance exercise. Such factors include timing of protein intake, dietary protein type, therole of leucine as a key anabolic amino acid, and the impact of other macronutrients (i.e.carbohydrate) on the regulation of MPS after resistance exercise. We contend that nutritionalstrategies that serve to maximally stimulate MPS may be useful in the development ofnutrition a...
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Effects of combined maternal administration with alpha-ketoglutarate (AKG) and beta-hydroxy-beta- methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring - Background: Nutritional manipulations during fetal growth may induce long-term metabolic effects inpostnatal life. The aim of the study was to test whether combined treatment of pregnant sowswith alpha-ketoglutarate and beta-hydroxy-beta-methylbutyrate induces additive long-term effectson skeletal system properties in the offspring. Methods: The study was performed on 290 pigs obtained from 24 sows divided into 4 equal groups andsubjected to experimental treatment during two weeks before delivery. The first groupconsisted of control sows, while the second group received alpha-ketoglutarate. The thirdgroup was treated with beta-hydroxy-beta-methylbutyrate and the fourth group underwentcombined administration of alpha-ketoglutarate and beta-hydroxy-beta-methylbutyrate. Pigletsobtained from sows were reared until slaughter age to perform morphometric, densitometricand mechanical analyses of femur. Serum evaluations of growth hormone, insulin-likegrowth factor-1, bone-specific alkaline pho...
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Substrate utilization during submaximal exercise in children with a severely obese parent - Background: We have reported a reduction in fatty acid oxidation (FAO) at the whole-body level and inskeletal muscle in severely obese (BMI [greater than or equal to] 40 kg/m2) individuals; this defect is retained in cellculture suggesting an inherent component. The purpose of the current study was to determineif an impairment in whole-body fatty acid oxidation (FAO) was also evident in children witha severely obese parent. Methods: Substrate utilization during submaximal exercise (cycle ergometer) was determined inchildren ages 8-12 y with a severely obese parent (OP, n = 13) or two lean/non-obese (BMIrange of 18 to 28 kg/m2) parents (LP, n = 13). A subgroup of subjects (n = 3/group)performed 4 weeks of exercise training with substrate utilization measured after theintervention. Results: The children did not differ in age (LP vs. OP, respectively) (10.7 +/- 0.5 vs. 10.2 +/- 0.5 y), BMIpercentile (65.3 +/- 5.2 vs. 75.9 +/- 7), Tanner Stage (1.4 +/- 0.2 vs. 1.5 +/- 0.2), VO2peak (40.3 +...
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Meju, unsalted soybeans fermented with Bacillus subtilis and Aspergilus oryzae, potentiates insulinotropic actions and improves hepatic insulin sensitivity in diabetic rats - Background: Although soybeans have the ability to attenuate insulin resistance, it is insufficient to alleviatetype 2 diabetic symptoms and different types of fermented soybeans may have even betteranti-diabetic effects. Meju, unsalted fermented soybeans exhibited better insulin sensitizingand insulinotropic actions than unfermented cooked soybeans (CSB). We investigatedwhether meju fermented in the traditional (TMS) manner for 60 days and meju fermented inthe standardized (MMS) method inoculating Bacillus subtilis and Aspergillus oryzae for 6days modulated insulin resistance, insulin secretion, and pancreatic beta-cell growth andsurvival in 90% pancreatectomized (Px) diabetic rats, a moderate and non-obese type 2diabetic animal model. Methods: Diabetic rats were divided into 3 groups: 1) TMS (n = 20), 2) MMS (n = 20) or 3) casein(control; n = 20). Rats were provided with a high fat diet (40 energy % fat) containingassigned 10% meju for 8 weeks. At the end of experiment insulin resista...
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Exploring metabolic dysfunction in chronic kidney disease - Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure andend-stage renal disease (ESRD) is a serious medical condition associated with increasedmorbidity, mortality, and in particular cardiovascular disease (CVD) risk. CKD is associatedwith multiple physiological and metabolic disturbances, including hypertension, dyslipidemiaand the anorexia-cachexia syndrome which are linked to poor outcomes. Specific hormonal,inflammatory, and nutritional-metabolic factors may play key roles in CKD development andpathogenesis. These include raised proinflammatory cytokines, such as interleukin-1 and 6,tumor necrosis factor, altered hepatic acute phase proteins, including reduced albumin,increased C-reactive protein, and perturbations in normal anabolic hormone responses withreduced growth hormone-insulin-like growth factor-1 axis activity. Others includehyperactivation of the renin-angiotensin aldosterone system (RAAS), with angiotensin II andaldosterone implicated in h...
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The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis - Background: Glutathione has a wide range of functions; it is an endogenous anti-oxidant and plays a key role in the maintenance of intracellular redox balance and detoxification of xenobiotics. Several studies have indicated that children with autism spectrum disorders may have altered glutathione metabolism which could play a key role in the condition. Methods: A systematic literature review and meta-analysis was conducted of studies examining metabolites, interventions and/or genes of the glutathione metabolism pathways i.e. the gamma-glutamyl cycle and trans-sulphuration pathway in autism spectrum disorders. Results: Thirty nine studies were included in the review comprising an in vitro study, thirty two metabolite and/or co-factor studies, six intervention studies and six studies with genetic data as well as eight studies examining enzyme activity. Conclusions: The review found evidence for the involvement of the gamma-glutamyl cycle and trans-sulphuration pathway in autistic disor...
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Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells - Background: N-3 polyunsaturated fatty acids, such as docosahexaenoic acid (DHA; 22:6n-3), has clinicalsignificance in the prevention and reversal of nonalcoholic steatohepatitis (NASH). However,the precious mechanism underlying remains unclear. The inflammasome, a multiproteincomplex formed by NOD-like receptor (NLR) family members, has been recently shown tobe activated in NASH and promote the cleavage of the pro-inflammatory cytokines to theirmaturation forms. Methods: HepG2 cells were exposed to different dose of PA for 24 h with or without the preincubationof 50 muM DHA for another 24 h and then lipid deposition was assessed with Oil red Ostaining and intracellular triglyceride (TG) determination. Secretory levels of inflammatorycytokines and Caspase-1 activity were determined by ELISA assays. Gene expression andprotein levels were determined by quantitative RCR and western blotting, respectively. Results: Palmitate (PA) dose-dependently increased lipid accumulation, TG content and...
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